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BMCBI
2010
190views more  BMCBI 2010»
15 years 7 months ago
APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Jun-Feng Xia, Xing-Ming Zhao, Jiangning Song, De-S...
BMCBI
2010
163views more  BMCBI 2010»
15 years 7 months ago
Reduced representation of protein structure: implications on efficiency and scope of detection of structural similarity
Background: Computational comparison of two protein structures is the starting point of many methods that build on existing knowledge, such as structure modeling (including modeli...
Zong Hong Zhang, Hwee Kuan Lee, Ivana Mihalek
BMCBI
2008
129views more  BMCBI 2008»
15 years 7 months ago
A unified approach to false discovery rate estimation
Background: False discovery rate (FDR) methods play an important role in analyzing highdimensional data. There are two types of FDR, tail area-based FDR and local FDR, as well as ...
Korbinian Strimmer
BMCBI
2008
134views more  BMCBI 2008»
15 years 7 months ago
Prediction of protein-protein binding site by using core interface residue and support vector machine
Background: The prediction of protein-protein binding site can provide structural annotation to the protein interaction data from proteomics studies. This is very important for th...
Nan Li, Zhonghua Sun, Fan Jiang
CAD
2008
Springer
15 years 7 months ago
Structure-oriented contour representation and matching for engineering shapes
Conventional shape matching for engineering models primarily considers rigid shape similarity. They do not seek global shape similarity while considering large local deformations....
Suyu Hou, Karthik Ramani
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