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ISMB
1997
15 years 7 months ago
Prediction of Enzyme Classification from Protein Sequence without the Use of Sequence Similarity
1 W’edescribe a novel approach for predicting the function of a protein from its amino-acid sequence. Given features that can be computedfrom the amino-acid sequence in a straigh...
Marie desJardins, Peter D. Karp, Markus Krummenack...
GECCO
2008
Springer
104views Optimization» more  GECCO 2008»
15 years 7 months ago
Protein-protein functional association prediction using genetic programming
Determining if a group of proteins are functionally associated among themselves is an open problem in molecular biology. Within our long term goal of applying Genetic Programming ...
Beatriz García, Ricardo Aler, Agapito Ledez...
CONSTRAINTS
2008
95views more  CONSTRAINTS 2008»
15 years 6 months ago
Efficient Sequence Alignment with Side-Constraints by Cluster Tree Elimination
Aligning DNA and protein sequences is a core technique in molecular biology. Often, it is desirable to include partial prior knowledge and conditions in an alignment. Going beyond...
Sebastian Will, Anke Busch, Rolf Backofen
BMCBI
2006
108views more  BMCBI 2006»
15 years 6 months ago
NOXclass: prediction of protein-protein interaction types
Background: Structural models determined by X-ray crystallography play a central role in understanding protein-protein interactions at the molecular level. Interpretation of these...
Hongbo Zhu, Francisco S. Domingues, Ingolf Sommer,...
BMCBI
2006
98views more  BMCBI 2006»
15 years 6 months ago
The Secrets of a Functional Synapse - From a Computational and Experimental Viewpoint
Background: Neuronal communication is tightly regulated in time and in space. The neuronal transmission takes place in the nerve terminal, at a specialized structure called the sy...
Michal Linial