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RECOMB
2005
Springer
16 years 6 months ago
Decomposition of Overlapping Protein Complexes: A Graph Theoretical Method for Analyzing Static and Dynamic Protein Associations
Background: Most cellular processes are carried out by multi-protein complexes, groups of proteins that bind together to perform a specific task. Some proteins form stable complex...
Elena Zotenko, Katia S. Guimarães, Raja Jot...
RECOMB
2005
Springer
16 years 6 months ago
Very Low Power to Detect Asymmetric Divergence of Duplicated Genes
Abstract. Asymmetric functional divergence of paralogues is a key aspect of the traditional model of evolution following duplication. If one gene continues to perform the ancestral...
Cathal Seoighe, Konrad Scheffler
BMCBI
2010
104views more  BMCBI 2010»
15 years 6 months ago
A method for automatically extracting infectious disease-related primers and probes from the literature
Background: Primer and probe sequences are the main components of nucleic acid-based detection systems. Biologists use primers and probes for different tasks, some related to the ...
Miguel García-Remesal, Alejandro Cuevas, Vi...
BMCBI
2008
118views more  BMCBI 2008»
15 years 6 months ago
Drug interaction prediction using ontology-driven hypothetical assertion framework for pathway generation followed by numerical
Background: In accordance with the increasing amount of information concerning individual differences in drug response and molecular interaction, the role of in silico prediction ...
Takeshi Arikuma, Sumi Yoshikawa, Ryuzo Azuma, Kent...
JMLR
2010
145views more  JMLR 2010»
15 years 1 months ago
Event based text mining for integrated network construction
The scientific literature is a rich and challenging data source for research in systems biology, providing numerous interactions between biological entities. Text mining technique...
Yvan Saeys, Sofie Van Landeghem, Yves Van de Peer