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RECOMB
2001
Springer
16 years 6 months ago
A new approach to sequence comparison: normalized sequence alignment
The Smith-Waterman algorithm for local sequence alignment is one of the most important techniques in computational molecular biology. This ingenious dynamic programming approach w...
Abdullah N. Arslan, Ömer Egecioglu, Pavel A. ...
SAC
2009
ACM
16 years 1 months ago
GTfold: a scalable multicore code for RNA secondary structure prediction
The prediction of the correct secondary structures of large RNAs is one of the unsolved challenges of computational molecular biology. Among the major obstacles is the fact that a...
Amrita Mathuriya, David A. Bader, Christine E. Hei...
ISMB
1993
15 years 7 months ago
Minimizing Complexity in Cellular Automata Models of Self-Replication
Understanding self-replication from an information processing perspective is important because, amongother things, it can shed light on molecular mechanismsof biological reproduct...
James A. Reggia, Hui-Hsien Chou, Steven L. Armentr...
BMCBI
2008
121views more  BMCBI 2008»
15 years 6 months ago
Modularization of biochemical networks based on classification of Petri net t-invariants
Background: Structural analysis of biochemical networks is a growing field in bioinformatics and systems biology. The availability of an increasing amount of biological data from ...
Eva Grafahrend-Belau, Falk Schreiber, Monika Heine...
BMCBI
2007
161views more  BMCBI 2007»
15 years 6 months ago
Efficient classification of complete parameter regions based on semidefinite programming
Background: Current approaches to parameter estimation are often inappropriate or inconvenient for the modelling of complex biological systems. For systems described by nonlinear ...
Lars Kuepfer, Uwe Sauer, Pablo A. Parrilo