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BMCBI
2008
226views more  BMCBI 2008»
15 years 6 months ago
ProteoLens: a visual analytic tool for multi-scale database-driven biological network data mining
Background: New systems biology studies require researchers to understand how interplay among myriads of biomolecular entities is orchestrated in order to achieve high-level cellu...
Tianxiao Huan, Andrey Y. Sivachenko, Scott H. Harr...
BMCBI
2004
104views more  BMCBI 2004»
15 years 6 months ago
Discriminative topological features reveal biological network mechanisms
Background: Recent genomic and bioinformatic advances have motivated the development of numerous network models intending to describe graphs of biological, technological, and soci...
Manuel Middendorf, Etay Ziv, Carter Adams, Jen Hom...
BMCBI
2006
116views more  BMCBI 2006»
15 years 6 months ago
Cluster analysis for DNA methylation profiles having a detection threshold
Background: DNA methylation, a molecular feature used to investigate tumor heterogeneity, can be measured on many genomic regions using the MethyLight technology. Due to the combi...
Paul Marjoram, Jing Chang, Peter W. Laird, Kimberl...
PVLDB
2010
152views more  PVLDB 2010»
15 years 4 months ago
k-Nearest Neighbors in Uncertain Graphs
Complex networks, such as biological, social, and communication networks, often entail uncertainty, and thus, can be modeled as probabilistic graphs. Similar to the problem of sim...
Michalis Potamias, Francesco Bonchi, Aristides Gio...
BIODATAMINING
2008
135views more  BIODATAMINING 2008»
15 years 6 months ago
Fast Gene Ontology based clustering for microarray experiments
Background: Analysis of a microarray experiment often results in a list of hundreds of diseaseassociated genes. In order to suggest common biological processes and functions for t...
Kristian Ovaska, Marko Laakso, Sampsa Hautaniemi