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BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
15 years 6 months ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
BMCBI
2006
144views more  BMCBI 2006»
15 years 6 months ago
Development and implementation of an algorithm for detection of protein complexes in large interaction networks
Background: After complete sequencing of a number of genomes the focus has now turned to proteomics. Advanced proteomics technologies such as two-hybrid assay, mass spectrometry e...
Md. Altaf-Ul-Amin, Yoko Shinbo, Kenji Mihara, Ken ...
CPM
2005
Springer
97views Combinatorics» more  CPM 2005»
15 years 11 months ago
On the Complexity of Sparse Exon Assembly
Gene structure prediction is one of the most important problems in computational molecular biology. It involves two steps: the first is finding the evidence (e.g. predicting spl...
Carmel Kent, Gad M. Landau, Michal Ziv-Ukelson
CCCG
2009
15 years 7 months ago
Defining and computing accessibility radius
In structural molecular biology software, the accessibility of an atom in a molecule to a ball representing solvent is either computed slowly by building a solventaccessible surfa...
Vishal Verma, Jack Snoeyink
BIB
2010
147views more  BIB 2010»
15 years 6 months ago
Toward the dynamic interactome: it's about time
Dynamic molecular interactions play a central role in regulating the functioning of cells and organisms.The availability of experimentally determined large-scale cellular networks...
Teresa M. Przytycka, Mona Singh, Donna K. Slonim