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ISOLA
2010
Springer
15 years 4 months ago
A Linked Data Approach to Sharing Workflows and Workflow Results
A bioinformatics analysis pipeline is often highly elaborate, due to the inherent complexity of biological systems and the variety and size of laboratory publications would be high...
Marco Roos, Sean Bechhofer, Jun Zhao, Paolo Missie...
RECOMB
2006
Springer
16 years 6 months ago
Simulating Protein Motions with Rigidity Analysis
Abstract. Protein motions, ranging from molecular flexibility to largescale conformational change, play an essential role in many biochemical processes. Despite the explosion in ou...
Shawna L. Thomas, Xinyu Tang, Lydia Tapia, Nancy M...
STOC
2006
ACM
129views Algorithms» more  STOC 2006»
16 years 6 months ago
Optimal phylogenetic reconstruction
One of the major tasks of evolutionary biology is the reconstruction of phylogenetic trees from molecular data. The evolutionary model is given by a Markov chain on the true evolu...
Constantinos Daskalakis, Elchanan Mossel, Sé...
CLADE
2008
IEEE
16 years 24 days ago
SWARM: a scientific workflow for supporting bayesian approaches to improve metabolic models
With the exponential growth of complete genome sequences, the analysis of these sequences is becoming a powerful approach to build genome-scale metabolic models. These models can ...
Xinghua Shi, Rick Stevens
ICCS
2001
Springer
15 years 10 months ago
High-Performance Algorithm Engineering for Computational Phylogenetics
Abstract. Phylogeny reconstruction from molecular data poses complex optimization problems: almost all optimization models are NP-hard and thus computationally intractable. Yet app...
Bernard M. E. Moret, David A. Bader, Tandy Warnow