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RECOMB
2010
Springer
15 years 11 months ago
SubMAP: Aligning Metabolic Pathways with Subnetwork Mappings
Abstract. We consider the problem of aligning two metabolic pathways. Unlike traditional approaches, we do not restrict the alignment to one-to-one mappings between the molecules o...
Ferhat Ay, Tamer Kahveci
ICCS
2001
Springer
15 years 10 months ago
High-Performance Algorithm Engineering for Computational Phylogenetics
Abstract. Phylogeny reconstruction from molecular data poses complex optimization problems: almost all optimization models are NP-hard and thus computationally intractable. Yet app...
Bernard M. E. Moret, David A. Bader, Tandy Warnow
BMCBI
2004
121views more  BMCBI 2004»
15 years 5 months ago
DEDB: a database of Drosophila melanogaster exons in splicing graph form
Background: A wealth of quality genomic and mRNA/EST sequences in recent years has provided the data required for large-scale genome-wide analysis of alternative splicing. We have...
Bernett T. K. Lee, Tin Wee Tan, Shoba Ranganathan
SIGMOD
2010
ACM
260views Database» more  SIGMOD 2010»
15 years 10 months ago
Towards proximity pattern mining in large graphs
Mining graph patterns in large networks is critical to a variety of applications such as malware detection and biological module discovery. However, frequent subgraphs are often i...
Arijit Khan, Xifeng Yan, Kun-Lung Wu
BMCBI
2010
142views more  BMCBI 2010»
15 years 6 months ago
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
Jongkwang Kim, Kai Tan