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IMSCCS
2006
IEEE
16 years 1 months ago
Combining Comparative Genomics with de novo Motif Discovery to Identify Human Transcription Factor DNA-Binding Motifs
Background: As more and more genomes are sequenced, comparative genomics approaches provide a methodology for identifying conserved regulatory elements that may be involved in gen...
Linyong Mao, W. Jim Zheng
IMSCCS
2006
IEEE
16 years 1 months ago
Clustering of Gene Expression Data: Performance and Similarity Analysis
Background: DNA Microarray technology is an innovative methodology in experimental molecular biology, which has produced huge amounts of valuable data in the profile of gene expre...
Longde Yin, Chun-Hsi Huang
PLDI
2006
ACM
16 years 29 days ago
Context-sensitive domain-independent algorithm composition and selection
Progressing beyond the productivity of present-day languages appears to require using domain-specific knowledge. Domain-specific languages and libraries (DSLs) proliferate, but ...
Troy A. Johnson, Rudolf Eigenmann
CIBCB
2005
IEEE
16 years 19 days ago
Toward Protein Structure Analysis with Self-Organizing Maps
- Establishing structure-function relationships on the proteomic scale is a unique challenge faced by bioinformatics and molecular biosciences. Large protein families represent nat...
Lutz Hamel, Gongqin Sun, Jing Zhang
CIKM
2005
Springer
16 years 16 days ago
Semantic similarity over the gene ontology: family correlation and selecting disjunctive ancestors
Many bioinformatics applications would benefit from comparing proteins based on their biological role rather than their sequence. In most biological databases, proteins are alrea...
Francisco M. Couto, Mário J. Silva, Pedro C...