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BMCBI
2006
120views more  BMCBI 2006»
15 years 7 months ago
Optimizing amino acid substitution matrices with a local alignment kernel
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
Hiroto Saigo, Jean-Philippe Vert, Tatsuya Akutsu
BMCBI
2006
121views more  BMCBI 2006»
15 years 7 months ago
Splice site identification using probabilistic parameters and SVM classification
Background: Recent advances and automation in DNA sequencing technology has created a vast amount of DNA sequence data. This increasing growth of sequence data demands better and ...
A. K. M. A. Baten, Bill C. H. Chang, Saman K. Halg...
BMCBI
2006
141views more  BMCBI 2006»
15 years 7 months ago
Asymptotic behaviour and optimal word size for exact and approximate word matches between random sequences
Background: The number of k-words shared between two sequences is a simple and effcient alignment-free sequence comparison method. This statistic, D2, has been used for the cluste...
Sylvain Forêt, Miriam R. Kantorovitz, Conrad...
BMCBI
2007
147views more  BMCBI 2007»
15 years 7 months ago
Bias in random forest variable importance measures: Illustrations, sources and a solution
Variable importance measures for random forests have been receiving increased attention as a means of variable selection in many classification tasks in bioinformatics and relate...
Carolin Strobl, Anne-Laure Boulesteix, Achim Zeile...
DKE
2007
130views more  DKE 2007»
15 years 7 months ago
Enabling access-privacy for random walk based data analysis applications
Random walk graph and Markov chain based models are used heavily in many data and system analysis domains, including web, bioinformatics, and queuing. These models enable the desc...
Ping Lin, K. Selçuk Candan