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APAL
2007
111views more  APAL 2007»
15 years 6 months ago
A coverage construction of the reals and the irrationals
I modify the standard coverage construction of the reals to obtain the irrationals. However, this causes a jump in ordinal complexity from ω + 1 to Ω. The coverage technique ha...
Harold Simmons
BMCBI
2010
116views more  BMCBI 2010»
15 years 6 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
BMCBI
2010
182views more  BMCBI 2010»
15 years 6 months ago
Beyond co-localization: inferring spatial interactions between sub-cellular structures from microscopy images
Background: Sub-cellular structures interact in numerous direct and indirect ways in order to fulfill cellular functions. While direct molecular interactions crucially depend on s...
Jo A. Helmuth, Grégory Paul, Ivo F. Sbalzar...
BMCBI
2007
144views more  BMCBI 2007»
15 years 6 months ago
Robust regression for periodicity detection in non-uniformly sampled time-course gene expression data
Background: In practice many biological time series measurements, including gene microarrays, are conducted at time points that seem to be interesting in the biologist's opin...
Miika Ahdesmäki, Harri Lähdesmäki, ...
CORR
2010
Springer
249views Education» more  CORR 2010»
15 years 6 months ago
Lower Bounds on Near Neighbor Search via Metric Expansion
In this paper we show how the complexity of performing nearest neighbor (NNS) search on a metric space is related to the expansion of the metric space. Given a metric space we loo...
Rina Panigrahy, Kunal Talwar, Udi Wieder