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187
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BMCBI
2005
107views more  BMCBI 2005»
15 years 6 months ago
ProbeMaker: an extensible framework for design of sets of oligonucleotide probes
Background: Procedures for genetic analyses based on oligonucleotide probes are powerful tools that can allow highly parallel investigations of genetic material. Such procedures r...
Johan Stenberg, Mats Nilsson, Ulf Landegren
201
Voted
BMCBI
2005
97views more  BMCBI 2005»
15 years 6 months ago
Modelling the correlation between the activities of adjacent genes in drosophila
Background: Correlation between the expression levels of genes which are located close to each other on the genome has been found in various organisms, including yeast, drosophila...
Helene H. Thygesen, Aeilko H. Zwinderman
201
Voted
BMCBI
2005
86views more  BMCBI 2005»
15 years 6 months ago
Chromosomal clustering of a human transcriptome reveals regulatory background
Background: There has been much evidence recently for a link between transcriptional regulation and chromosomal gene order, but the relationship between genomic organization, regu...
Jan H. Vogel, Anja von Heydebreck, Antje Purmann, ...
170
Voted
BMCBI
2005
169views more  BMCBI 2005»
15 years 6 months ago
An adaptive method for cDNA microarray normalization
Background: Normalization is a critical step in analysis of gene expression profiles. For duallabeled arrays, global normalization assumes that the majority of the genes on the ar...
Yingdong Zhao, Ming-Chung Li, Richard Simon
216
Voted
BMCBI
2005
151views more  BMCBI 2005»
15 years 6 months ago
ProMiner: rule-based protein and gene entity recognition
Background: Identification of gene and protein names in biomedical text is a challenging task as the corresponding nomenclature has evolved over time. This has led to multiple syn...
Daniel Hanisch, Katrin Fundel, Heinz-Theodor Mevis...
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