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» Gene Expression Data Management: A Case Study
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BMCBI
2008
142views more  BMCBI 2008»
15 years 6 months ago
Microarray data mining: A novel optimization-based approach to uncover biologically coherent structures
Background: DNA microarray technology allows for the measurement of genome-wide expression patterns. Within the resultant mass of data lies the problem of analyzing and presenting...
Meng Piao Tan, Erin N. Smith, James R. Broach, Chr...
ISMB
2007
15 years 8 months ago
A Chado case study: an ontology-based modular schema for representing genome-associated biological information
Motivation: A few years ago, FlyBase undertook to design a new database schema to store Drosophila data. It would fully integrate genomic sequence and annotation data with bibliog...
Chris Mungall, David B. Emmert
BMCBI
2006
203views more  BMCBI 2006»
15 years 6 months ago
Independent component analysis reveals new and biologically significant structures in micro array data
Background: An alternative to standard approaches to uncover biologically meaningful structures in micro array data is to treat the data as a blind source separation (BSS) problem...
Attila Frigyesi, Srinivas Veerla, David Lindgren, ...
IEEECIT
2005
IEEE
15 years 11 months ago
Case Study: Distance-Based Image Retrieval in the MoBIoS DBMS
Similarity search leveraging distance-based index structures is increasingly being used for complex data types. It has been shown that for high dimensional uniform vectors with si...
Rui Mao, Wenguo Liu, Daniel P. Miranker, Qasim Iqb...
BMCBI
2007
78views more  BMCBI 2007»
15 years 6 months ago
Improved human disease candidate gene prioritization using mouse phenotype
Background: The majority of common diseases are multi-factorial and modified by genetically and mechanistically complex polygenic interactions and environmental factors. High-thro...
Jing Chen, Huan Xu, Bruce J. Aronow, Anil G. Jegga