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» Gene Expression Data Management: A Case Study
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BMCBI
2008
82views more  BMCBI 2008»
15 years 6 months ago
Studying the functional conservation of cis-regulatory modules and their transcriptional output
Background: Cis-regulatory modules (CRMs) are distinct, genomic regions surrounding the target gene that can independently activate the promoter to drive transcription. The activa...
Denis C. Bauer, Timothy L. Bailey
BMCBI
2010
125views more  BMCBI 2010»
15 years 6 months ago
Asymmetric microarray data produces gene lists highly predictive of research literature on multiple cancer types
Background: Much of the public access cancer microarray data is asymmetric, belonging to datasets containing no samples from normal tissue. Asymmetric data cannot be used in stand...
Noor B. Dawany, Aydin Tozeren
BMCBI
2006
88views more  BMCBI 2006»
15 years 6 months ago
A two-sample Bayesian t-test for microarray data
Background: Determining whether a gene is differentially expressed in two different samples remains an important statistical problem. Prior work in this area has featured the use ...
Richard J. Fox, Matthew W. Dimmic
BMCBI
2010
84views more  BMCBI 2010»
15 years 6 months ago
An integrated analysis of molecular aberrations in NCI-60 cell lines
Background: Cancer is a complex disease where various types of molecular aberrations drive the development and progression of malignancies. Large-scale screenings of multiple type...
Chen-Hsiang Yeang
ISI
2004
Springer
15 years 11 months ago
West Nile Virus and Botulism Portal: A Case Study in Infectious Disease Informatics
Abstract. Information technologies and infectious disease informatics are playing an increasingly important role in preventing, detecting, and managing infectious disease outbreaks...
Daniel Dajun Zeng, Hsinchun Chen, Chunju Tseng, Ca...