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» Gene Expression Data Management: A Case Study
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BMCBI
2006
138views more  BMCBI 2006»
15 years 6 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
BMCBI
2004
180views more  BMCBI 2004»
15 years 6 months ago
Noise filtering and nonparametric analysis of microarray data underscores discriminating markers of oral, prostate, lung, ovaria
Background: A major goal of cancer research is to identify discrete biomarkers that specifically characterize a given malignancy. These markers are useful in diagnosis, may identi...
Virginie M. Aris, Michael J. Cody, Jeff Cheng, Jam...
SIGMOD
2007
ACM
151views Database» more  SIGMOD 2007»
16 years 6 months ago
The case for a wide-table approach to manage sparse relational data sets
A "sparse" data set typically has hundreds or even thousands of attributes, but most objects have non-null values for only a small number of these attributes. A popular ...
Eric Chu, Jennifer L. Beckmann, Jeffrey F. Naughto...
BMCBI
2007
129views more  BMCBI 2007»
15 years 6 months ago
HoughFeature, a novel method for assessing drug effects in three-color cDNA microarray experiments
Background: Three-color microarray experiments can be performed to assess drug effects on the genomic scale. The methodology may be useful in shortening the cycle, reducing the co...
Hongya Zhao, Hong Yan
BMCBI
2010
126views more  BMCBI 2010»
15 years 6 months ago
GeneBrowser 2: an application to explore and identify common biological traits in a set of genes
Background: The development of high-throughput laboratory techniques created a demand for computer-assisted result analysis tools. Many of these techniques return lists of genes w...
Joel Arrais, João Fernandes, João Pe...