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» Gene Expression Data Management: A Case Study
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BMCBI
2006
116views more  BMCBI 2006»
15 years 6 months ago
Cluster analysis for DNA methylation profiles having a detection threshold
Background: DNA methylation, a molecular feature used to investigate tumor heterogeneity, can be measured on many genomic regions using the MethyLight technology. Due to the combi...
Paul Marjoram, Jing Chang, Peter W. Laird, Kimberl...
BMCBI
2010
124views more  BMCBI 2010»
15 years 6 months ago
Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regu
Background: Comprehensively understanding corticosteroid pharmacogenomic effects is an essential step towards an insight into the underlying molecular mechanisms for both benefici...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2005
115views more  BMCBI 2005»
15 years 6 months ago
MPrime: efficient large scale multiple primer and oligonucleotide design for customized gene microarrays
Background: Enhancements in sequencing technology have recently yielded assemblies of large genomes including rat, mouse, human, fruit fly, and zebrafish. The availability of larg...
Eric C. Rouchka, Abdelnaby Khalyfa, Nigel G. F. Co...
ESWS
2007
Springer
15 years 10 months ago
Towards Novel Techniques for Reasoning in Expressive Description Logics based on Binary Decision Diagrams
We propose to design and study new techniques for description logic (DL) reasoning based on a prominent data structure that has been applied very successfully in various domains in...
Uwe Keller
POLICY
2004
Springer
15 years 11 months ago
Cassandra: Distributed Access Control Policies with Tunable Expressiveness
We study the specification of access control policy in large-scale distributed systems. Our work on real-world policies has shown that standard policy idioms such as role hierarc...
Moritz Y. Becker, Peter Sewell