The biological interpretation of large-scale gene expression data is one of the challenges in current bioinformatics. The state-of-theart approach is to perform clustering and then...
Italo Zoppis, Daniele Merico, Marco Antoniotti, Bu...
Abstract. The responses of flexible bionetworks to extreme environmental changes were studied in several microorganisms. Gene and metabolic networks markedly changed with osmotic ...
Background: Microarray experimentation requires the application of complex analysis methods as well as the use of non-trivial computer technologies to manage the resultant large d...
Geraint Barton, J. C. Abbott, Norie Chiba, D. W. H...
Background: Extracting biological information from high-density Affymetrix arrays is a multi-step process that begins with the accurate annotation of microarray probes. Shortfalls...
Jun Lu, Joseph C. Lee, Marc L. Salit, Margaret C. ...
Background: Eukaryotic cells have developed mechanisms to respond to external environmental or physiological changes (stresses). In order to increase the activities of stress-prot...