Background: It has been repeatedly observed that gene order is rapidly lost in prokaryotic genomes. However, persistent synteny blocks are found when comparing more or less distan...
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Recently, some non-coding small RNAs, known as microRNAs (miRNA), have drawn a lot of attention to identify their role in gene regulation and various biological processes. The miRN...
Background: In many approaches to the inference and modeling of regulatory interactions using microarray data, the expression of the gene coding for the transcription factor is co...
Background: Expressed sequence tags (ESTs) analyses are a fundamental tool for gene identification in organisms. Given a preliminary EST sample from a certain library, several sta...