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164
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BMCBI
2010
15 years 6 months ago
2010
Background: The development of DNA microarrays has facilitated the generation of hundreds of thousands of transcriptomic datasets. The use of a common reference microarray design ...
207
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BMCBI
2007
15 years 6 months ago
2007
Background: Recent analyses have suggested that many genes possess multiple transcription start sites (TSSs) that are differentially utilized in different tissues and cell lines. ...
153
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BMCBI
2007
15 years 6 months ago
2007
Background: The combination of mass spectrometry and solution phase amide hydrogen/deuterium exchange (H/D exchange) experiments is an effective method for characterizing protein ...
163
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BMCBI
2007
15 years 6 months ago
2007
Background: RNA metabolism, through 'combinatorial splicing', can generate enormous structural diversity in the proteome. Alternative domains may interact, however, with...
213
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BMCBI
2008
15 years 6 months ago
2008
Background: Significance analysis at single gene level may suffer from the limited number of samples and experimental noise that can severely limit the power of the chosen statist...