Background: The development of algorithms to infer the structure of gene regulatory networks based on expression data is an important subject in bioinformatics research. Validatio...
Tim Van den Bulcke, Koen Van Leemput, Bart Naudts,...
Background: That the structure determines the function of proteins is a central paradigm in biology. However, protein functions are more directly related to cooperative effects at...
Background: Two-dimensional data colourings are an effective medium by which to represent three-dimensional data in two dimensions. Such "color-grid" representations hav...
Marcin P. Joachimiak, Jennifer L. Weissman, Barnab...
Background: Differentially expressed genes are typically identified by analyzing the variation between replicate measurements. These procedures implicitly assume that there are no...
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...