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BMCBI
2008
160views more  BMCBI 2008»
15 years 6 months ago
A comparison of four clustering methods for brain expression microarray data
Background: DNA microarrays, which determine the expression levels of tens of thousands of genes from a sample, are an important research tool. However, the volume of data they pr...
Alexander L. Richards, Peter Holmans, Michael C. O...
BMCBI
2008
188views more  BMCBI 2008»
15 years 6 months ago
anNET: a tool for network-embedded thermodynamic analysis of quantitative metabolome data
Background: Compared to other omics techniques, quantitative metabolomics is still at its infancy. Complex sample preparation and analytical procedures render exact quantification...
Nicola Zamboni, Anne Kümmel, Matthias Heinema...
BMCBI
2008
143views more  BMCBI 2008»
15 years 6 months ago
catmap: Case-control And TDT Meta-Analysis Package
Background: Risk for complex disease is thought to be controlled by multiple genetic risk factors, each with small individual effects. Meta-analyses of several independent studies...
Kristin K. Nicodemus
BMCBI
2008
110views more  BMCBI 2008»
15 years 6 months ago
Enhancing the prediction of protein pairings between interacting families using orthology information
Background: It has repeatedly been shown that interacting protein families tend to have similar phylogenetic trees. These similarities can be used to predicting the mapping betwee...
José M. G. Izarzugaza, David de Juan, Carle...
BMCBI
2008
140views more  BMCBI 2008»
15 years 6 months ago
SCPRED: Accurate prediction of protein structural class for sequences of twilight-zone similarity with predicting sequences
Background: Protein structure prediction methods provide accurate results when a homologous protein is predicted, while poorer predictions are obtained in the absence of homologou...
Lukasz A. Kurgan, Krzysztof J. Cios, Ke Chen 0003
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