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BMCBI
2004
177views more  BMCBI 2004»
15 years 6 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
BMCBI
2004
134views more  BMCBI 2004»
15 years 6 months ago
Bayesian model accounting for within-class biological variability in Serial Analysis of Gene Expression (SAGE)
Background: An important challenge for transcript counting methods such as Serial Analysis of Gene Expression (SAGE), "Digital Northern" or Massively Parallel Signature ...
Ricardo Z. N. Vêncio, Helena Brentani, Diogo...
JCB
2000
103views more  JCB 2000»
15 years 6 months ago
Testing for Differentially-Expressed Genes by Maximum-Likelihood Analysis of Microarray Data
Although two-color uorescent DNA microarrays are now standard equipment in many molecular biology laboratories, methods for identifying differentially expressed genes in microarra...
Trey Ideker, Vesteinn Thorsson, Andrew F. Siegel, ...
SIAMAM
2000
128views more  SIAMAM 2000»
15 years 6 months ago
Advection-Diffusion Equations for Internal State-Mediated Random Walks
Abstract. In many biological examples of biased random walks, movement statistics are determined by state dynamics that are internal to the organism or cell and that mediate respon...
Daniel Grünbaum
BC
1998
58views more  BC 1998»
15 years 6 months ago
Detecting multimodality in saccadic reaction time distributions in gap and overlap tasks
In many cases the distribution of saccadic reaction times (SRT) deviates considerably from a unimodal distribution and may often exhibit several peaks. We present a statistical app...
Stefan Gezeck, Jens Timmer