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BMCBI
2005
118views more  BMCBI 2005»
15 years 6 months ago
Vestige: Maximum likelihood phylogenetic footprinting
Background: Phylogenetic footprinting is the identification of functional regions of DNA by their evolutionary conservation. This is achieved by comparing orthologous regions from...
Matthew J. Wakefield, Peter Maxwell, Gavin A. Hutt...
JBI
2007
120views Bioinformatics» more  JBI 2007»
15 years 6 months ago
Measures of semantic similarity and relatedness in the biomedical domain
Measures of semantic similarity between concepts are widely used in Natural Language Processing. In this article, we show how six existing domain-independent measures can be adapt...
Ted Pedersen, Serguei V. S. Pakhomov, Siddharth Pa...
JCB
2007
198views more  JCB 2007»
15 years 6 months ago
Bayesian Hierarchical Model for Large-Scale Covariance Matrix Estimation
Many bioinformatics problems can implicitly depend on estimating large-scale covariance matrix. The traditional approaches tend to give rise to high variance and low accuracy esti...
Dongxiao Zhu, Alfred O. Hero III
BMCBI
2005
125views more  BMCBI 2005»
15 years 6 months ago
Query3d: a new method for high-throughput analysis of functional residues in protein structures
Background: The identification of local similarities between two protein structures can provide clues of a common function. Many different methods exist for searching for similar ...
Gabriele Ausiello, Allegra Via, Manuela Helmer-Cit...
TPDS
2008
140views more  TPDS 2008»
15 years 6 months ago
High-Performance Resource Allocation and Request Redirection Algorithms for Web Clusters
Abstract-- With increasing richness in features such as personalization of content, web applications are becoming more complex and hence compute intensive. Traditional approaches t...
Supranamaya Ranjan, Edward W. Knightly
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