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BMCBI
2007
128views more  BMCBI 2007»
15 years 6 months ago
Absolute estimation of initial concentrations of amplicon in a real-time RT-PCR process
Background: Since real time PCR was first developed, several approaches to estimating the initial quantity of template in an RT-PCR reaction have been tried. While initially only ...
Marjo V. Smith, Chris R. Miller, Michael Kohn, Nig...
BMCBI
2007
108views more  BMCBI 2007»
15 years 6 months ago
Publishing perishing? Towards tomorrow's information architecture
Scientific articles are tailored to present information in human-readable aliquots. Although the Internet has revolutionized the way our society thinks about information, the trad...
Michael R. Seringhaus, Mark B. Gerstein
BMCBI
2008
149views more  BMCBI 2008»
15 years 6 months ago
Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment s
Background: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic d...
Olivier Bastien, Eric Maréchal
BMCBI
2006
111views more  BMCBI 2006»
15 years 6 months ago
SIMMAP: Stochastic character mapping of discrete traits on phylogenies
Background: Character mapping on phylogenies has played an important, if not critical role, in our understanding of molecular, morphological, and behavioral evolution. Until very ...
Jonathan P. Bollback
BMCBI
2006
136views more  BMCBI 2006»
15 years 6 months ago
Java GUI for InterProScan (JIPS): A tool to help process multiple InterProScans and perform ortholog analysis
Background: Recent, rapid growth in the quantity of available genomic data has generated many protein sequences that are not yet biochemically classified. Thus, the prediction of ...
Aijazuddin Syed, Chris Upton