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BMCBI
2004
208views more  BMCBI 2004»
15 years 6 months ago
Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
Vadim Alexandrov, Mark Gerstein
BMCBI
2004
131views more  BMCBI 2004»
15 years 6 months ago
Alternative mapping of probes to genes for Affymetrix chips
Background: Short oligonucleotide arrays have several probes measuring the expression level of each target transcript. Therefore the selection of probes is a key component for the...
Laurent Gautier, Morten Møller, Lennart Fri...
BMCBI
2004
150views more  BMCBI 2004»
15 years 6 months ago
Rank Difference Analysis of Microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data
Background: A key step in the analysis of microarray expression profiling data is the identification of genes that display statistically significant changes in expression signals ...
Dietmar E. Martin, Philippe Demougin, Michael N. H...
BMCBI
2004
141views more  BMCBI 2004»
15 years 6 months ago
Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
Ruslan Sadreyev, Nick V. Grishin
CG
2004
Springer
15 years 6 months ago
Refereed digital publication of computer graphics educational materials
Computer Graphics as a discipline has undergone drastic modifications over the past decades. Indeed the phenomenal progress in both the technical and digital art domains requires ...
Frederico C. Figueiredo, Dena Elisabeth Eber, Joaq...
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