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177
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BMCBI
2010
15 years 6 months ago
2010
Background: An algorithm is presented to compute a multiple structure alignment for a set of proteins and to generate a consensus (pseudo) protein which captures common substructu...
156
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BMCBI
2010
15 years 6 months ago
2010
Background: Knowledge-based potentials have been widely used in the last 20 years for fold recognition, protein structure prediction from amino acid sequence, ligand binding, prot...
178
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BMCBI
2010
15 years 6 months ago
2010
Background: The large amount of high-throughput genomic data has facilitated the discovery of the regulatory relationships between transcription factors and their target genes. Wh...
188
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BMCBI
2008
15 years 6 months ago
2008
Background: Illumina Infinium whole genome genotyping (WGG) arrays are increasingly being applied in cancer genomics to study gene copy number alterations and allele-specific aber...
188
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BMCBI
2006
15 years 6 months ago
2006
Background: Large-scale genetic mapping projects require data management systems that can handle complex phenotypes and detect and correct high-throughput genotyping errors, yet a...