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BMCBI
2010
124views more  BMCBI 2010»
15 years 6 months ago
Estimation and efficient computation of the true probability of recurrence of short linear protein sequence motifs in unrelated
Background: Large datasets of protein interactions provide a rich resource for the discovery of Short Linear Motifs (SLiMs) that recur in unrelated proteins. However, existing met...
Norman E. Davey, Richard J. Edwards, Denis C. Shie...
BMCBI
2008
94views more  BMCBI 2008»
15 years 6 months ago
Structural assembly of two-domain proteins by rigid-body docking
Background: Modelling proteins with multiple domains is one of the central challenges in Structural Biology. Although homology modelling has successfully been applied for predicti...
Tammy M. K. Cheng, Tom L. Blundell, Juan Fern&aacu...
BMCBI
2010
138views more  BMCBI 2010»
15 years 6 months ago
Sigma-2: Multiple sequence alignment of non-coding DNA via an evolutionary model
Background: While most multiple sequence alignment programs expect that all or most of their input is known to be homologous, and penalise insertions and deletions, this is not a ...
Gayathri Jayaraman, Rahul Siddharthan
KDD
2002
ACM
170views Data Mining» more  KDD 2002»
16 years 7 months ago
On interactive visualization of high-dimensional data using the hyperbolic plane
: se the concept of visualizing general abstract data by intermediate projection into the hyperbolic space. Its favorable properties were reported earlier and led to the "hype...
Helge Ritter, Jörg A. Walter
AAAI
2008
15 years 9 months ago
An Architecture and Formalism for Handling Modular Ontologies
The goal of my ongoing work is to provide an architecture for developing and manipulating modular ontologies in such a way that each ontology module can plug into or unplug from a...
Faezeh Ensan