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BMCBI
2011
15 years 1 months ago
Errors in CGAP xProfiler and cDNA DGED: the importance of library parsing and gene selection algorithms
Background: The Cancer Genome Anatomy Project (CGAP) xProfiler and cDNA Digital Gene Expression Displayer (DGED) have been made available to the scientific community over a decade...
Andrew T. Milnthorpe, Mikhail Soloviev
ISBI
2011
IEEE
14 years 10 months ago
Network cycle features: Application to computer-aided Gleason grading of prostate cancer histopathological images
Features extracted from cell networks have become popular tools in histological image analysis. However, existing features do not take sufficient advantage of the cycle structure...
Parmeshwar Khurd, Leo Grady, Ali Kamen, Summer Gib...
BMCBI
2011
14 years 10 months ago
Biomarker Discovery and Redundancy Reduction towards Classification using a Multi-factorial MALDI-TOF MS T2DM Mouse Model Datase
Background: Diabetes like many diseases and biological processes is not mono-causal. On the one hand multifactorial studies with complex experimental design are required for its c...
Chris Bauer, Frank Kleinjung, Celia J. Smith, Mark...
BMCBI
2011
14 years 10 months ago
Proportion statistics to detect differentially expressed genes: a comparison with log-ratio statistics
Background: In genetic transcription research, gene expression is typically reported in a test sample relative to a reference sample. Laboratory assays that measure gene expressio...
Tracy L. Bergemann, Jason Wilson
BMCBI
2011
14 years 10 months ago
In-silico prediction of disorder content using hybrid sequence representation
Background: Intrinsically disordered proteins play important roles in various cellular activities and their prevalence was implicated in a number of human diseases. The knowledge ...
Marcin J. Mizianty, Tuo Zhang, Bin Xue, Yaoqi Zhou...