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» Framework for a Protein Ontology
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BMCBI
2008
120views more  BMCBI 2008»
15 years 6 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...
BMCBI
2005
126views more  BMCBI 2005»
15 years 6 months ago
HomoMINT: an inferred human network based on orthology mapping of protein interactions discovered in model organisms
Background: The application of high throughput approaches to the identification of protein interactions has offered for the first time a glimpse of the global interactome of some ...
Maria Persico, Arnaud Ceol, Caius Gavrila, Robert ...
GCC
2006
Springer
15 years 10 months ago
Grid Enabled Data Integration Framework for Bioinformatics Research
A framework is proposed to manage the distributed and heterogeneous databases in grid environment for understanding protein-protein interaction. Furthermore, the framework is used...
Jia Liu, Yongwei Wu, Weimin Zheng
AO
2006
127views more  AO 2006»
15 years 6 months ago
Formal ontology meets industry
in ontology is quite abstract and often based on toy-examples to the point that the gap between the work of theoreticians and the needs of real applications is too wide to be cross...
Stefano Borgo, Matteo Cristani, Roberta Cuel
BMCBI
2006
130views more  BMCBI 2006»
15 years 6 months ago
Identifying biological concepts from a protein-related corpus with a probabilistic topic model
Background: Biomedical literature, e.g., MEDLINE, contains a wealth of knowledge regarding functions of proteins. Major recurring biological concepts within such text corpora repr...
Bin Zheng, David C. McLean Jr, Xinghua Lu