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BMCBI
2006
139views more  BMCBI 2006»
15 years 6 months ago
Improvement in accuracy of multiple sequence alignment using novel group-to-group sequence alignment algorithm with piecewise li
Background: Multiple sequence alignment (MSA) is a useful tool in bioinformatics. Although many MSA algorithms have been developed, there is still room for improvement in accuracy...
Shinsuke Yamada, Osamu Gotoh, Hayato Yamana
CPHYSICS
2006
204views more  CPHYSICS 2006»
15 years 6 months ago
Genetically controlled random search: a global optimization method for continuous multidimensional functions
A new stochastic method for locating the global minimum of a multidimensional function inside a rectangular hyperbox is presented. A sampling technique is employed that makes use ...
Ioannis G. Tsoulos, Isaac E. Lagaris
BMCBI
2002
101views more  BMCBI 2002»
15 years 6 months ago
Total sequence decomposition distinguishes functional modules, "molegos" in apurinic/apyrimidinic endonucleases
Background: Total sequence decomposition, using the web-based MASIA tool, identifies areas of conservation in aligned protein sequences. By structurally annotating these motifs, t...
Catherine H. Schein, Numan Özgün, Tadahi...
BMCBI
2011
14 years 10 months ago
FFCA: a feasibility-based method for flux coupling analysis of metabolic networks
Background: Flux coupling analysis (FCA) is a useful method for finding dependencies between fluxes of a metabolic network at steady-state. FCA classifies reactions into subsets (...
László Dávid, Sayed-Amir Mara...
ICSE
2011
IEEE-ACM
14 years 10 months ago
Always-available static and dynamic feedback
Developers who write code in a statically typed language are denied the ability to obtain dynamic feedback by executing their code during periods when it fails the static type che...
Michael Bayne, Richard Cook, Michael D. Ernst