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BMCBI
2008
102views more  BMCBI 2008»
15 years 6 months ago
PhyloNet: a software package for analyzing and reconstructing reticulate evolutionary relationships
Background: Phylogenies, i.e., the evolutionary histories of groups of taxa, play a major role in representing the interrelationships among biological entities. Many software tool...
Cuong Than, Derek A. Ruths, Luay Nakhleh
BMCBI
2008
80views more  BMCBI 2008»
15 years 6 months ago
Towards an automatic classification of protein structural domains based on structural similarity
Background: Formal classification of a large collection of protein structures aids the understanding of evolutionary relationships among them. Classifications involving manual ste...
Vichetra Sam, Chin-Hsien Tai, Jean Garnier, Jean-F...
BMCBI
2008
138views more  BMCBI 2008»
15 years 6 months ago
Methods for simultaneously identifying coherent local clusters with smooth global patterns in gene expression profiles
Background: The hierarchical clustering tree (HCT) with a dendrogram [1] and the singular value decomposition (SVD) with a dimension-reduced representative map [2] are popular met...
Yin-Jing Tien, Yun-Shien Lee, Han-Ming Wu, Chun-Ho...
BMCBI
2008
134views more  BMCBI 2008»
15 years 6 months ago
Clustering cancer gene expression data: a comparative study
Background The use of clustering methods for the discovery of cancer subtypes has drawn a great deal of attention in the scientific community. While bioinformaticians have propose...
Marcílio Carlos Pereira de Souto, Ivan G. C...
BMCBI
2008
128views more  BMCBI 2008»
15 years 6 months ago
Validation of an NSP-based (negative selection pattern) gene family identification strategy
Background: Gene family identification from ESTs can be a valuable resource for analysis of genome evolution but presents unique challenges in organisms for which the entire genom...
Ronald L. Frank, Cyriac Kandoth, Fikret Erç...