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BMCBI
2010
110views more  BMCBI 2010»
15 years 6 months ago
Missing value imputation for epistatic MAPs
Background: Epistatic miniarray profiling (E-MAPs) is a high-throughput approach capable of quantifying aggravating or alleviating genetic interactions between gene pairs. The dat...
Colm Ryan, Derek Greene, Gerard Cagney, Padraig Cu...
BMCBI
2010
111views more  BMCBI 2010»
15 years 6 months ago
Comparative performances of DNA barcoding across insect orders
Background: Previous studies on insect DNA barcoding provide contradictory results and suggest not consistent performances across orders. This work aims at providing a general eva...
Massimiliano Virgilio, Thierry Backeljau, Bruno Ne...
BMCBI
2010
214views more  BMCBI 2010»
15 years 6 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
BMCBI
2010
161views more  BMCBI 2010»
15 years 6 months ago
GATExplorer: Genomic and Transcriptomic Explorer; mapping expression probes to gene loci, transcripts, exons and ncRNAs
Background: Genome-wide expression studies have developed exponentially in recent years as a result of extensive use of microarray technology. However, expression signals are typi...
Alberto Risueño, Celia Fontanillo, Marcel E...
BMCBI
2010
120views more  BMCBI 2010»
15 years 6 months ago
KiDoQ: using docking based energy scores to develop ligand based model for predicting antibacterials
Background: Identification of novel drug targets and their inhibitors is a major challenge in the field of drug designing and development. Diaminopimelic acid (DAP) pathway is a u...
Aarti Garg, Rupinder Tewari, Gajendra P. S. Raghav...