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ADCS
2004
15 years 8 months ago
Focused Crawling in Depression Portal Search: A Feasibility Study
Previous work on domain specific search services in the area of depressive illness has documented the significant human cost required to setup and maintain closed-crawl parameters....
Thanh Tin Tang, David Hawking, Nick Craswell, Rame...
BMCBI
2010
109views more  BMCBI 2010»
15 years 6 months ago
Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
Andrew J. Bordner, Hans D. Mittelmann
BMCBI
2006
94views more  BMCBI 2006»
15 years 6 months ago
Metabolite coupling in genome-scale metabolic networks
Background: Biochemically detailed stoichiometric matrices have now been reconstructed for various bacteria, yeast, and for the human cardiac mitochondrion based on genomic and pr...
Scott A. Becker, Nathan D. Price, Bernhard O. Pals...
BMCBI
2006
91views more  BMCBI 2006»
15 years 6 months ago
Cheminformatics methods for novel nanopore analysis of HIV DNA termini
Background: Channel current feature extraction methods, using Hidden Markov Models (HMMs) have been designed for tracking individual-molecule conformational changes. This informat...
Stephen Winters-Hilt, Matthew Landry, Mark Akeson,...
BMCBI
2006
137views more  BMCBI 2006»
15 years 6 months ago
Genome BLAST distance phylogenies inferred from whole plastid and whole mitochondrion genome sequences
Background: Phylogenetic methods which do not rely on multiple sequence alignments are important tools in inferring trees directly from completely sequenced genomes. Here, we exte...
Alexander F. Auch, Stefan R. Henz, Barbara R. Holl...