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» Focusing on Binding and Computation
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ICFP
2010
ACM
15 years 7 months ago
A fresh look at programming with names and binders
A wide range of computer programs, including compilers and theorem provers, manipulate data structures that involve names and binding. However, the design of programming idioms wh...
Nicolas Pouillard, François Pottier
BIB
2008
113views more  BIB 2008»
15 years 6 months ago
Identification of replication origins in prokaryotic genomes
The availability of hundreds of complete bacterial genomes has created new challenges and simultaneously opportunities for bioinformatics. In the area of statistical analysis of g...
Natalia V. Sernova, Mikhail S. Gelfand
BMCBI
2010
116views more  BMCBI 2010»
15 years 6 months ago
Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences
Background: Precise and efficient methods for gene targeting are critical for detailed functional analysis of genomes and regulatory networks and for potentially improving the eff...
Jeffry D. Sander, Deepak Reyon, Morgan L. Maeder, ...
ENTCS
2010
127views more  ENTCS 2010»
15 years 6 months ago
Combining Model Reductions
Molecular biological models usually suffer from a large combinatorial explosion. Indeed, proteins form complexes and modify each others, which leads to the formation of a huge num...
Ferdinanda Camporesi, Jérôme Feret, H...
JCC
2008
132views more  JCC 2008»
15 years 6 months ago
The implementation of a fast and accurate QM/MM potential method in Amber
Abstract: Version 9 of the Amber simulation programs includes a new semi-empirical hybrid QM/MM functionality. This includes support for implicit solvent (generalized Born) and for...
Ross C. Walker, Michael F. Crowley, David A. Case