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BMCBI
2008
83views more  BMCBI 2008»
15 years 6 months ago
Prioritization of gene regulatory interactions from large-scale modules in yeast
Background: The identification of groups of co-regulated genes and their transcription factors, called transcriptional modules, has been a focus of many studies about biological s...
Ho-Joon Lee, Thomas Manke, Ricardo Bringas, Martin...
BMCBI
2005
126views more  BMCBI 2005»
15 years 6 months ago
GANN: Genetic algorithm neural networks for the detection of conserved combinations of features in DNA
Background: The multitude of motif detection algorithms developed to date have largely focused on the detection of patterns in primary sequence. Since sequence-dependent DNA struc...
Robert G. Beiko, Robert L. Charlebois
BIB
2010
140views more  BIB 2010»
15 years 3 months ago
Next generation sequencing in functional genomics
Genome-wide sequencing has enabled modern biomedical research to relate more and more events in healthy as well as disease-affected cells and tissues to the genomic sequence. Now ...
Thomas Werner
SC
2009
ACM
16 years 1 months ago
FPGA-based acceleration of CHARMM-potential minimization
Energy minimization is an important step in molecular modeling, with applications in molecular docking and in mapping binding sites. Minimization involves repeated evaluation of v...
Bharat Sukhwani, Martin C. Herbordt
FMOODS
2007
15 years 7 months ago
Model Checking of Extended OCL Constraints on UML Models in SOCLe
We present the first tool that offers dynamic verification of extended traints on UML models. It translates a UML model into an Abstract State (ASM) which is transformed by an AS...
John Mullins, Raveca Oarga