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186
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BMCBI
2008
15 years 6 months ago
2008
Background: It has been repeatedly observed that gene order is rapidly lost in prokaryotic genomes. However, persistent synteny blocks are found when comparing more or less distan...
155
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BMCBI
2008
15 years 6 months ago
2008
teps. First, we abstracted protein interactions onto orthologous cluster links. For a given source interaction, if both proteins belonged to a cluster, we constructed a link betwee...
188
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BMCBI
2006
15 years 6 months ago
2006
Background: In the post-genome era, most research scientists working in the field of proteomics are confronted with difficulties in management of large volumes of data, which they...
175
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CCR
2006
15 years 6 months ago
2006
The rapid growth of the Internet over the last decade has been startling. However, efforts to track its growth have often fallen afoul of bad data -- for instance, how much traffi...
190
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JIB
2006
15 years 6 months ago
2006
3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...