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BMCBI
2008
161views more  BMCBI 2008»
15 years 6 months ago
Inferring gene expression dynamics via functional regression analysis
Background: Temporal gene expression profiles characterize the time-dynamics of expression of specific genes and are increasingly collected in current gene expression experiments....
Hans-Georg Müller, Jeng-Min Chiou, Xiaoyan Le...
BMCBI
2008
97views more  BMCBI 2008»
15 years 6 months ago
Large-scale directional relationship extraction and resolution
Background: Relationships between entities such as genes, chemicals, metabolites, phenotypes and diseases in MEDLINE are often directional. That is, one may affect the other in a ...
Cory B. Giles, Jonathan D. Wren
BMCBI
2006
213views more  BMCBI 2006»
15 years 6 months ago
CoXpress: differential co-expression in gene expression data
Background: Traditional methods of analysing gene expression data often include a statistical test to find differentially expressed genes, or use of a clustering algorithm to find...
Michael Watson
BMCBI
2006
87views more  BMCBI 2006»
15 years 6 months ago
Phylogeny based discovery of regulatory elements
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
Jason Gertz, Justin C. Fay, Barak A. Cohen
BMCBI
2010
110views more  BMCBI 2010»
15 years 6 months ago
Discovering local patterns of co - evolution: computational aspects and biological examples
Background: Co-evolution is the process in which two (or more) sets of orthologs exhibit a similar or correlative pattern of evolution. Co-evolution is a powerful way to learn abo...
Tamir Tuller, Yifat Felder, Martin Kupiec