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BMCBI
2006
114views more  BMCBI 2006»
15 years 6 months ago
A methodology for global validation of microarray experiments
Background: DNA microarrays are popular tools for measuring gene expression of biological samples. This ever increasing popularity is ensuring that a large number of microarray st...
Mathieu Miron, Owen Z. Woody, Alexandre Marcil, Ca...
BMCBI
2006
84views more  BMCBI 2006»
15 years 6 months ago
Inferring topology from clustering coefficients in protein-protein interaction networks
Background: Although protein-protein interaction networks determined with high-throughput methods are incomplete, they are commonly used to infer the topology of the complete inte...
Caroline C. Friedel, Ralf Zimmer
BMCBI
2007
194views more  BMCBI 2007»
15 years 6 months ago
A meta-data based method for DNA microarray imputation
Background: DNA microarray experiments are conducted in logical sets, such as time course profiling after a treatment is applied to the samples, or comparisons of the samples unde...
Rebecka Jörnsten, Ming Ouyang, Hui-Yu Wang
BMCBI
2007
123views more  BMCBI 2007»
15 years 6 months ago
Robust clustering in high dimensional data using statistical depths
Background: Mean-based clustering algorithms such as bisecting k-means generally lack robustness. Although componentwise median is a more robust alternative, it can be a poor cent...
Yuanyuan Ding, Xin Dang, Hanxiang Peng, Dawn Wilki...
IOR
2008
126views more  IOR 2008»
15 years 6 months ago
Fast Simulation of Multifactor Portfolio Credit Risk
This paper develops rare event simulation methods for the estimation of portfolio credit risk -- the risk of losses to a portfolio resulting from defaults of assets in the portfol...
Paul Glasserman, Wanmo Kang, Perwez Shahabuddin