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BMCBI
2010
136views more  BMCBI 2010»
15 years 6 months ago
A hub-attachment based method to detect functional modules from confidence-scored protein interactions and expression profiles
Background: Many research results show that the biological systems are composed of functional modules. Members in the same module usually have common functions. This is useful inf...
Chia-Hao Chin, Shu-Hwa Chen, Chin-Wen Ho, Ming-Tat...
BMCBI
2008
97views more  BMCBI 2008»
15 years 6 months ago
A Population Proportion approach for ranking differentially expressed genes
Background: DNA microarrays are used to investigate differences in gene expression between two or more classes of samples. Most currently used approaches compare mean expression l...
Mugdha Gadgil
BMCBI
2007
166views more  BMCBI 2007»
15 years 6 months ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang
BMCBI
2007
108views more  BMCBI 2007»
15 years 6 months ago
Publishing perishing? Towards tomorrow's information architecture
Scientific articles are tailored to present information in human-readable aliquots. Although the Internet has revolutionized the way our society thinks about information, the trad...
Michael R. Seringhaus, Mark B. Gerstein
BMCBI
2008
130views more  BMCBI 2008»
15 years 6 months ago
Function approximation approach to the inference of reduced NGnet models of genetic networks
Background: The inference of a genetic network is a problem in which mutual interactions among genes are deduced using time-series of gene expression patterns. While a number of m...
Shuhei Kimura, Katsuki Sonoda, Soichiro Yamane, Hi...