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BMCBI
2010
109views more  BMCBI 2010»
15 years 6 months ago
Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
Background: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a comple...
Xiaojiang Xu, Stephen Hoang, Marty W. Mayo, Stefan...
BMCBI
2010
135views more  BMCBI 2010»
15 years 6 months ago
Quadratic variance models for adaptively preprocessing SELDI-TOF mass spectrometry data
Background: Surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI) is a proteomics tool for biomarker discovery and other high throughput applicatio...
Vincent A. Emanuele II, Brian M. Gurbaxani
JCB
2006
129views more  JCB 2006»
15 years 6 months ago
GenRate: A Generative Model that Reveals Novel Transcripts in Genome-Tiling Microarray Data
Genome-wide microarray designs containing millions to hundreds of millions of probes are available for a variety of mammals, including mouse and human. These genome tiling arrays ...
Brendan J. Frey, Quaid Morris, Timothy R. Hughes
SIGIR
2008
ACM
15 years 6 months ago
A user browsing model to predict search engine click data from past observations
Search engine click logs provide an invaluable source of relevance information but this information is biased because we ignore which documents from the result list the users have...
Georges Dupret, Benjamin Piwowarski
BMCBI
2005
151views more  BMCBI 2005»
15 years 6 months ago
stam - a Bioconductor compliant R package for structured analysis of microarray data
Background: Genome wide microarray studies have the potential to unveil novel disease entities. Clinically homogeneous groups of patients can have diverse gene expression profiles...
Claudio Lottaz, Rainer Spang