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BMCBI
2006
133views more  BMCBI 2006»
15 years 6 months ago
Topological basis of signal integration in the transcriptional-regulatory network of the yeast, Saccharomyces cerevisiae
Background: Signal recognition and information processing is a fundamental cellular function, which in part involves comprehensive transcriptional regulatory (TR) mechanisms carri...
Illés J. Farkas, Chuang Wu, Chakra Chennubh...
BMCBI
2006
156views more  BMCBI 2006»
15 years 6 months ago
Detecting the limits of regulatory element conservation and divergence estimation using pairwise and multiple alignments
Background: Molecular evolutionary studies of noncoding sequences rely on multiple alignments. Yet how multiple alignment accuracy varies across sequence types, tree topologies, d...
Daniel A. Pollard, Alan M. Moses, Venky N. Iyer, M...
BMCBI
2007
105views more  BMCBI 2007»
15 years 6 months ago
Finding regulatory elements and regulatory motifs: a general probabilistic framework
Over the last two decades a large number of algorithms has been developed for regulatory motif finding. Here we show how many of these algorithms, especially those that model bind...
Erik van Nimwegen
SPEECH
1998
69views more  SPEECH 1998»
15 years 6 months ago
Noisy speech enhancement using discrete cosine transform
This paper illustrates the advantages of using the Discrete Cosine Transform (DCT) as compared to the standard Discrete Fourier Transform (DFT) for the purpose of removing noise e...
Ing Yann Soon, Soo Ngee Koh, Chai Kiat Yeo
BMCBI
2010
191views more  BMCBI 2010»
15 years 1 months ago
Molecular dynamics simulation studies and in vitro site directed mutagenesis of avian beta-defensin Apl_AvBD2
Background: Defensins comprise a group of antimicrobial peptides, widely recognized as important elements of the innate immune system in both animals and plants. Cationicity, rath...
Soja Saghar Soman, Krishnankutty Chandrika Sivakum...