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BMCBI
2008
111views more  BMCBI 2008»
15 years 6 months ago
Information-based methods for predicting gene function from systematic gene knock-downs
Background: The rapid annotation of genes on a genome-wide scale is now possible for several organisms using high-throughput RNA interference assays to knock down the expression o...
Matthew T. Weirauch, Christopher K. Wong, Alexandr...
BMCBI
2006
157views more  BMCBI 2006»
15 years 6 months ago
Determination of the minimum number of microarray experiments for discovery of gene expression patterns
Background: One type of DNA microarray experiment is discovery of gene expression patterns for a cell line undergoing a biological process over a series of time points. Two import...
Fang-Xiang Wu, W. J. Zhang, Anthony J. Kusalik
BMCBI
2006
118views more  BMCBI 2006»
15 years 6 months ago
Gene Expression Profiles Distinguish the Carcinogenic Effects of Aristolochic Acid in Target (Kidney) and Non-target (Liver) Tis
Background: Aristolochic acid (AA) is the active component of herbal drugs derived from Aristolochia species that have been used for medicinal purposes since antiquity. AA, howeve...
Tao Chen, Lei Guo, Lu Zhang 0013, Leming M. Shi, H...
IMSCCS
2006
IEEE
16 years 13 days ago
Degenerated Primer Design to Amplify the Heavy Chain Variable Region from Immunoglobulin cDNA
Background: The amplification of variable regions of immunoglobulins has become a major challenge in the cloning of antibody genes, whether from hybridoma cell lines or splenic B ...
Wang Ying, Chen Wei, Li Xu, Cheng Bing
BMCBI
2008
82views more  BMCBI 2008»
15 years 6 months ago
Gene expression profile of peripheral blood mononuclear cells in response to HIV-VLPs stimulation
Background: Baculovirus-expressed HIV-1 Pr55gag Virus-Like Particles (HIV-VLPs) induce maturation and activation of monocyte-derived dendritic cells (MDDCs) with a production of T...
Luigi Buonaguro, Alessandro Monaco, Eleonora Aric&...