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IWANN
2009
Springer
16 years 28 days ago
GREAT: Gene Regulation EvAluation Tool
Our understanding of biological systems is highly dependent on the study of the mechanisms that regulate genetic expression. In this paper we present a tool to evaluate scientific ...
Catia Machado, Hugo P. Bastos, Francisco M. Couto
BMCBI
2006
93views more  BMCBI 2006»
15 years 6 months ago
A summarization approach for Affymetrix GeneChip data using a reference training set from a large, biologically diverse database
Background: Many of the most popular pre-processing methods for Affymetrix expression arrays, such as RMA, gcRMA, and PLIER, simultaneously analyze data across a set of predetermi...
Simon Katz, Rafael A. Irizarry, Xue Lin, Mark Trip...
AINA
2008
IEEE
16 years 26 days ago
Missing Value Estimation for Time Series Microarray Data Using Linear Dynamical Systems Modeling
The analysis of gene expression time series obtained from microarray experiments can be effectively exploited to understand a wide range of biological phenomena from the homeostat...
Connie Phong, Raul Singh
BMCBI
2011
14 years 10 months ago
Reconstructing genome-wide regulatory network of E. coli using transcriptome data and predicted transcription factor activities
Background: Gene regulatory networks play essential roles in living organisms to control growth, keep internal metabolism running and respond to external environmental changes. Un...
Yao Fu, Laura R. Jarboe, Julie A. Dickerson
BMCBI
2007
168views more  BMCBI 2007»
15 years 6 months ago
GOSim - an R-package for computation of information theoretic GO similarities between terms and gene products
Background: With the increased availability of high throughput data, such as DNA microarray data, researchers are capable of producing large amounts of biological data. During the...
Holger Fröhlich, Nora Speer, Annemarie Poustk...