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BMCBI
2007
129views more  BMCBI 2007»
15 years 6 months ago
HoughFeature, a novel method for assessing drug effects in three-color cDNA microarray experiments
Background: Three-color microarray experiments can be performed to assess drug effects on the genomic scale. The methodology may be useful in shortening the cycle, reducing the co...
Hongya Zhao, Hong Yan
ICDE
2004
IEEE
133views Database» more  ICDE 2004»
16 years 7 months ago
GenExplore: Interactive Exploration of Gene Interactions from Microarray Data
DNA Microarray provides a powerful basis for analysis of gene expression. Data mining methods such as clustering have been widely applied to microarray data to link genes that sho...
Yong Ye, Xintao Wu, Kalpathi R. Subramanian, Liyin...
IJBRA
2007
89views more  IJBRA 2007»
15 years 6 months ago
Conservative adjustment of permutation p-values when the number of permutations is limited
The permutation procedure is widely used to assess the significance level (p-value) of a test statistic. This approach is asymptotically consistent. In genomics and proteomics st...
Yinglei Lai
IPPS
2003
IEEE
15 years 11 months ago
Gene Clustering Using Self-Organizing Maps and Particle Swarm Optimization
Gene clustering, the process of grouping related genes in the same cluster, is at the foundation of different genomic studies that aim at analyzing the function of genes. Microarr...
Xiang Xiao, Ernst R. Dow, Russell C. Eberhart, Zin...
BMCBI
2008
82views more  BMCBI 2008»
15 years 6 months ago
Studying the functional conservation of cis-regulatory modules and their transcriptional output
Background: Cis-regulatory modules (CRMs) are distinct, genomic regions surrounding the target gene that can independently activate the promoter to drive transcription. The activa...
Denis C. Bauer, Timothy L. Bailey