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BMCBI
2010
122views more  BMCBI 2010»
15 years 6 months ago
Fast and accurate protein substructure searching with simulated annealing and GPUs
Background: Searching a database of protein structures for matches to a query structure, or occurrences of a structural motif, is an important task in structural biology and bioin...
Alex Stivala, Peter J. Stuckey, Anthony Wirth
BMCBI
2007
166views more  BMCBI 2007»
15 years 6 months ago
Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Xinning Jiang, Xiaogang Jiang, Guanghui Han, Mingl...
BMCBI
2007
162views more  BMCBI 2007»
15 years 6 months ago
Bioclipse: an open source workbench for chemo- and bioinformatics
Background: There is a need for software applications that provide users with a complete and extensible toolkit for chemo- and bioinformatics accessible from a single workbench. C...
Ola Spjuth, Tobias Helmus, Egon L. Willighagen, St...
BMCBI
2008
79views more  BMCBI 2008»
15 years 6 months ago
A high-throughput pipeline for designing microarray-based pathogen diagnostic assays
Background: We present a methodology for high-throughput design of oligonucleotide fingerprints for microarray-based pathogen diagnostic assays. The oligonucleotide fingerprints, ...
Ravi Vijaya Satya, Nela Zavaljevski, Kamal Kumar, ...
BMCBI
2007
156views more  BMCBI 2007»
15 years 6 months ago
Bio: : NEXUS: a Perl API for the NEXUS format for comparative biological data
Background: Evolutionary analysis provides a formal framework for comparative analysis of genomic and other data. In evolutionary analysis, observed data are treated as the termin...
Thomas Hladish, Vivek Gopalan, Chengzhi Liang, Wei...
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