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BMCBI
2005
152views more  BMCBI 2005»
15 years 6 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
BMCBI
2005
86views more  BMCBI 2005»
15 years 6 months ago
WebArray: an online platform for microarray data analysis
Background: Many cutting-edge microarray analysis tools and algorithms, including commonly used limma and affy packages in Bioconductor, need sophisticated knowledge of mathematic...
Xiaoqin Xia, Michael McClelland, Yipeng Wang
TKDE
2008
125views more  TKDE 2008»
15 years 6 months ago
Discovering and Explaining Abnormal Nodes in Semantic Graphs
An important problem in the area of homeland security is to identify abnormal or suspicious entities in large datasets. Although there are methods from data mining and social netwo...
Shou-de Lin, Hans Chalupsky
BMCBI
2005
178views more  BMCBI 2005»
15 years 6 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
JCB
2007
144views more  JCB 2007»
15 years 6 months ago
Statistical Estimation of Statistical Mechanical Models: Helix-Coil Theory and Peptide Helicity Prediction
Analysis of biopolymer sequences and structures generally adopts one of two approaches: use of detailed biophysical theoretical models of the system with experimentally-determined...
Scott C. Schmidler, Joseph E. Lucas, Terrence G. O...
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