Background: The main aim of this study was to develop and implement an algorithm for the rapid, accurate and automated identification of paths leading from buried protein clefts, ...
Background: Although protein-protein interaction networks determined with high-throughput methods are incomplete, they are commonly used to infer the topology of the complete inte...
Background: The most fundamental task using gene expression data in clinical oncology is to classify tissue samples according to their gene expression levels. Compared with tradit...
Background: An important class of interaction switches for biological circuits and disease pathways are short binding motifs. However, the biological experiments to find these bin...
Soon-Heng Tan, Hugo Willy, Wing-Kin Sung, See-Kion...
Affymetrix microarrays have become a standard experimental platform for studies of mRNA expression profiling. Their success is due, in part, to the multiple oligonucleotide featur...