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210
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BMCBI
2008
15 years 6 months ago
2008
Background: Normalization is essential in dual-labelled microarray data analysis to remove nonbiological variations and systematic biases. Many normalization methods have been use...
193
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BMCBI
2007
15 years 6 months ago
2007
Background: Joint alignment and secondary structure prediction of two RNA sequences can significantly improve the accuracy of the structural predictions. Methods addressing this p...
184
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BMCBI
2008
15 years 6 months ago
2008
Background: High-density short oligonucleotide microarrays are a primary research tool for assessing global gene expression. Background noise on microarrays comprises a significan...
169
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BMCBI
2007
15 years 6 months ago
2007
Background: In many laboratory-based high throughput microarray experiments, there are very few replicates of gene expression levels. Thus, estimates of gene variances are inaccur...
155
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BMCBI
2008
15 years 6 months ago
2008
Background: An important aspect of proteomic mass spectrometry involves quantifying and interpreting the isotope distributions arising from mixtures of macromolecules with differe...