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BMCBI
2010
135views more  BMCBI 2010»
15 years 7 months ago
Integration and visualization of systems biology data in context of the genome
Background: High-density tiling arrays and new sequencing technologies are generating rapidly increasing volumes of transcriptome and protein-DNA interaction data. Visualization a...
J. Christopher Bare, Tie Koide, David J. Reiss, Da...
BMCBI
2007
134views more  BMCBI 2007»
15 years 7 months ago
Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign
Background: Joint alignment and secondary structure prediction of two RNA sequences can significantly improve the accuracy of the structural predictions. Methods addressing this p...
Arif Ozgun Harmanci, Gaurav Sharma, David H. Mathe...
EM
2010
155views Management» more  EM 2010»
15 years 7 months ago
Hyperbolic Graphs of Small Complexity
In this paper we enumerate and classify the "simplest" pairs (M, G) where M is a closed orientable 3-manifold and G is a trivalent graph embedded in M. To enumerate the p...
Damian Heard, Craig Hodgson, Bruno Martelli, Carlo...
BMCBI
2006
108views more  BMCBI 2006»
15 years 7 months ago
RibAlign: a software tool and database for eubacterial phylogeny based on concatenated ribosomal protein subunits
Background: Until today, analysis of 16S ribosomal RNA (rRNA) sequences has been the de-facto gold standard for the assessment of phylogenetic relationships among prokaryotes. How...
Hanno Teeling, Frank Oliver Glöckner
BMCBI
2006
158views more  BMCBI 2006»
15 years 7 months ago
Detection of non-coding RNAs on the basis of predicted secondary structure formation free energy change
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
Andrew V. Uzilov, Joshua M. Keegan, David H. Mathe...
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