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BMCBI
2005
107views more  BMCBI 2005»
15 years 7 months ago
ProbeMaker: an extensible framework for design of sets of oligonucleotide probes
Background: Procedures for genetic analyses based on oligonucleotide probes are powerful tools that can allow highly parallel investigations of genetic material. Such procedures r...
Johan Stenberg, Mats Nilsson, Ulf Landegren
BMCBI
2005
169views more  BMCBI 2005»
15 years 7 months ago
An adaptive method for cDNA microarray normalization
Background: Normalization is a critical step in analysis of gene expression profiles. For duallabeled arrays, global normalization assumes that the majority of the genes on the ar...
Yingdong Zhao, Ming-Chung Li, Richard Simon
202
Voted
BMCBI
2004
124views more  BMCBI 2004»
15 years 7 months ago
XHM: A system for detection of potential cross hybridizations in DNA microarrays
Background: Microarrays have emerged as the preferred platform for high throughput gene expression analysis. Cross-hybridization among genes with high sequence similarities can be...
Kristian Flikka, Fekadu Yadetie, Astrid Lægr...
BMCBI
2004
141views more  BMCBI 2004»
15 years 7 months ago
Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
Ruslan Sadreyev, Nick V. Grishin
CIKM
2010
Springer
15 years 5 months ago
Examining the information retrieval process from an inductive perspective
Term-weighting functions derived from various models of retrieval aim to model human notions of relevance more accurately. However, there is a lack of analysis of the sources of e...
Ronan Cummins, Mounia Lalmas, Colm O'Riordan
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